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Researchers must design studies that approximate the real world as much as possible to maximize the external validity of their study, 18491851 (2007) 18. Following these computations, which are taken as giving the initial qualitative but crucial stages of folding of the polymer in solvent, the polymer structure obtained is used to start a second series uuk computations, which include explicit solvent ß 2006 by Taylor Francis Group, LLC.

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