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torex. 5 Carboxy-cyclopropyl and cyclobutyl analogues A related series of L-2-(2-carboxycyclobutyl)glycines (CBGs) was recently prepared using an aspartate aminotransferase in a chemo-enzymatic synthe- sis rengan assessed for EAAT activity with a FLIPR-based membrane potential assay [71, 72]. These instruments will be used with likely increasing frequency in future clini- cal studies to assess outcomes of diverse treatment options.
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